Recombinant Anti-CD35 Antibody [CR1/8833R] (A314689)

Anti-CD35 Antibody [CR1/8833R]

Recombinant rabbit monoclonal [CR1/8833R] antibody to CD35.

CD35, complement receptor 1, is a cell membrane-bound, monomeric glycoprotein on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils, and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.

Follicular dendritic cells (FDC) in tonsil.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 600-900) of human CR1 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

CR1/8833R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

224 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

C3 binding protein, C3b/C4b receptor, C3BR, C4BR, CD 35, CD35 antigen, complement component (3b/4b) receptor 1 (Knops blood group), complement component (3b/4b) receptor 1 including Knops blood group system, Complement component receptor 1, Complement receptor 1, Complement receptor type 1, CR 1, CR1, CR1_HUMAN, KN, Knops blood group antigen