Anti-CD62P Antibody [AK-6] (A279660)

$340

Mouse monoclonal [AK-6] antibody to CD62P for WB, IHC-P, IF, Flow Cytometry and IHC-Fr.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-CD62P Antibody [AK-6]
Description
Mouse monoclonal [AK-6] antibody to CD62P.
Specificity
This antibody recognises the CD62P, also known as P-selectin, Granule membrane protein 140, GMP140, Leukocyte-endothelial cell adhesion molecule 3 or Platelet activation dependent granule-external membrane protein. CD62P is a 830 amino acid, including a 41 amino acid signal peptide, ~140 kDa single pass type I transmembrane glycoprotein expressed on activated platelets and endothelial cellCD62P plays an important role in adhesive processes between leucocytes and endothelial cells. CD62P is a component of the platelet alpha granule and is rapidly translocated to the plasma membrane upon activation.
Applications
WB, IHC-P, IF, Flow Cytometry, IHC-Fr
Dilutions
Flow Cytometry: 1:10 - 1:100, IHC-Fr: 1:1,000 - 1:5,000, IHC-P: 1:500 - 1:2,000, Use 10µl of the suggested working dilution to label 106 cells in 100µl. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections but staining may be enhanced using Sodium Citrate buffer pH6.0
Reactivity
Human, Rhesus Monkey
Immunogen
Human platelet membrane glycoproteins.
Host
Mouse
Clonality
Monoclonal
Clone ID
AK-6
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human CD62P antibody, clone AK-6 recognizes the CD62P, also known as P-selectin, Granule membrane protein 140, GMP140, Leukocyte-endothelial cell adhesion molecule 3 or Platelet activation dependent granule-external membrane protein. CD62P is a 830 amino acid, including a 41 amino acid signal peptide, ~140 kDa single pass type I transmembrane glycoprotein expressed on activated platelets and endothelial cellCD62P plays an important role in adhesive processes between leucocytes and endothelial cells. CD62P is a component of the platelet alpha granule and is rapidly translocated to the plasma membrane upon activation (Stenberg et al. 1985).
Synonyms
Antigen CD62, CD62, CD62 antigen like family member P, CD62 antigen-like family member P, FLJ45155, GMP 140, GMP-140, GMP140, GMRP, Granule membrane protein 140, Granule membrane protein 140kDa, Granulocyte membrane protein, GRMP, LECAM 3, LECAM3, Leukocyte endothelial cell adhesion molecule 3 , Leukocyte-endothelial cell adhesion molecule 3, LYAM3_HUMAN, P selectin, P-selectin, PADGEM, Platelet activation dependent granule external membrane protein, Platelet activation dependent granule-external membrane protein, Platelet alpha granule membrane protein, PSEL, Selectin P, Selectin P (granule membrane protein 140kDa antigen CD62), Selectin P (granule membrane protein 140kDa, antigen CD62), SELP
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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