Anti-Chromogranin A Antibody [LK2H10] (A280876)

Anti-Chromogranin A Antibody [LK2H10]

Mouse monoclonal [LK2H10] antibody to Chromogranin A.

This antibody recognises chromogranin A (CgA), a secretory glycoprotein and member of the chromogranin/secretogranin family, widely expressed by cells of the neuroendocrine system and related tumours, which is used in immunohistochemistry as a valuable diagnostic marker for pheochromocytomas, paragangliomas and carcinoid, pancreatic and prostate tumours. CgA constitutes one of the most abundant components of secretory granules, and is the precursor to several functional peptides, including vasostatin and pancreastatin. Clone LK2H10 has been shown to be suitable for use on cytospins.

WB, IHC-P, IHC-Fr

IHC-P 1: 1:100 - 1:500

Human, Pig, Monkey

Human pheochromocytoma tissue.

Mouse

Monoclonal

LK2H10

IgG1

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human Chromogranin A antibody, clone LK2H10 specifically recognizes chromogranin A (CgA), a secretory glycoprotein and member of the chromogranin/secretogranin family, widely expressed by cells of the neuroendocrine system and related tumours, which is used in immunohistochemistry as a valuable diagnostic marker for pheochromocytomas, paragangliomas and carcinoid, pancreatic and prostate tumours. CgA constitutes one of the most abundant components of secretory granules, and is the precursor to several functional peptides, including vasostatin and pancreastatin. Clone LK2H10 has been shown to be suitable for use on cytospins (Jensen et al. 1990).

beta Granin, betagranin (N-terminal fragment of chromogranin A), catestatin, CgA, CHG A, Chga, chromofungin, Chromogranin A parathyroid secretory protein 1, Chromogranin A precursor, ChromograninA, CMGA_HUMAN, ER-37, Pancreastatin, Parastatin, Parathyroid secretory protein 1, Pituitary secretory protein I, Secretory protein I, SP I, SP-I, SP1, SPI, Vasostatin, Vasostatin I, Vasostatin II