Anti-D-Dimer Antibody [DD6] (A280234)

Anti-D-Dimer Antibody [DD6]

Mouse monoclonal [DD6] antibody to D-Dimer.

This antibody recognises human D-dimer and shows low cross-reactivity with fibrinogen (D-monomer).D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease.

ELISA, WB

Human

Homogenised fibrin clot.

Mouse

Monoclonal

DD6

IgG2a

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human D-Dimer antibody, clone DD6 recognizes human D-dimer and shows low cross-reactivity with fibrinogen (D-monomer).D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease.

D Dimer