Anti-DAZL Antibody [3/11A] (A279247)

$855

Mouse monoclonal [3/11A] antibody to DAZL for WB, IHC-P and IF.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-DAZL Antibody [3/11A]
Description
Mouse monoclonal [3/11A] antibody to DAZL.
Specificity
This antibody recognises human Deleted in azoospermia-like, also known as DAZL, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1 or SPGY-like-autosomal. DAZL is a 295 amino acid ~33 kDa member of the DAZ (deleted in azoospermia) family of RNA binding proteins. DAZL is expressed in fetal and adult testes and ovaries, and is believed to play a role in germ cell development. In adult germ cells, the expression of DAZL is predominantly localized to the cytoplasm.Mutations in this gene have been linked to severe spermatogenic failure and infertility in males
Applications
WB, IHC-P, IF
Reactivity
Human, Mouse, Rat, Cynomolgus monkey
Immunogen
Synthetic peptide sequence CRVHHFRRSRAMLKSV from within the C-terminus of human DAZL.
Sequence
CRVHHFRRSRAMLKSV
Host
Mouse
Clonality
Monoclonal
Clone ID
3/11A
Isotype
IgG1
Conjugate

Unconjugated

Concentration
Lot Specific
Purity
Tissue Culture Supernatant containing 0.1M Tris/HCl
Product Form
Liquid
Formulation
Supplied in <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human DAZL antibody, clone 3/11A recognizes human Deleted in azoospermia-like, also known as DAZL, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1 or SPGY-like-autosomal. DAZL is a 295 amino acid ~33 kDa member of the DAZ (deleted in azoospermia) family of RNA binding proteins. DAZL is expressed in fetal and adult testes and ovaries, and is believed to play a role in germ cell development. In adult germ cells, the expression of DAZL is predominantly localized to the cytoplasm.Mutations in this gene have been linked to severe spermatogenic failure and infertility in males (Lin et al. 2001)
Synonyms
DAZ homolog, DAZ like autosomal, DAZ-like autosomal, DAZH, DAZL 1, DAZL1, DAZLA, DAZL_HUMAN, Deleted in azoospermia like, Deleted in azoospermia like 1, Deleted in azoospermia like autosomal, Deleted in azoospermia-like, Deleted in azoospermia-like 1, Germline specific RNA binding protein, MGC26406, Spermatogenesis gene on the Y like autosomal, SPGY like autosomal, SPGY-like-autosomal, SPGYLA, Tpx2
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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