Anti-EIF2S1 Antibody [PCRP-EIF2S1-1C11] - BSA and Azide free (A251595)

Mouse monoclonal [PCRP-EIF2S1-1C11] antibody to EIF2S1 for Flow Cytometry.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-EIF2S1 Antibody [PCRP-EIF2S1-1C11] - BSA and Azide free
Description
Mouse monoclonal [PCRP-EIF2S1-1C11] antibody to EIF2S1.
Specificity
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex is composed of three subunits, designated eIF2a, eIF2band eIF2g (eukaryotic translation initiation factor 2 a, band g, respectively), all of which work in concert to form a ternary complex with GTP and tRNA in the early stages of protein synthesis. eIF2a, also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP-dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2a controls the rate of tRNA translation. When eIF2a is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2a is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation.
Applications
Flow Cytometry
Dilutions
Flow Cytometry: 1-2 µg/million cells
Reactivity
Human
Cross Reactivity
This antibody is predicted to cross react with Rat and Zebrafish.
Immunogen
Recombinant full-length human EIF2S1 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-EIF2S1-1C11
Isotype
IgG2a
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
36 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-EIF2S1 Antibody [PCRP-EIF2S1-1C11] (A248413).
Synonyms
EIF 2, EIF 2 alpha, EIF 2A, EIF 2alpha, eIF-2-alpha, eIF-2A, EIF-2alpha, EIF2, EIF2 alpha, EIF2A, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 1 alpha, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, Eukaryotic translation initiation factor 2 subunit alpha, IF2A_HUMAN
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Anti-EIF2S1 Antibody [PCRP-EIF2S1-1C11] - BSA and Azide free (A251595)? Please let us know so that we can list the citation on this page.

Alternative products to Anti-EIF2S1 Antibody [PCRP-EIF2S1-1C11] - BSA and Azide free (A251595)

Top