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Anti-FADD Antibody

Rabbit polyclonal antibody to FADD from ABclonal (A0759).
Name: Anti-FADD Antibody
Description: Rabbit polyclonal antibody to FADD.
Applications: WB
Dilutions: WB: 1:500 - 1:1000.
Reactivity: Human
Immunogen: A synthetic peptide of human FADD.
Protein Length: 208
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Tissue Specificity: Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
Involvement in Disease: Infections, recurrent, associated with encephalopathy, hepatic dysfunction and cardiovascular malformations: A condition with biological features of autoimmune lymphoproliferative syndrome such as high-circulating CD4(-)CD8(-)TCR-alpha-beta(+) T-cell counts, and elevated IL10 and FASL levels. Affected individuals suffer from recurrent, stereotypical episodes of fever, encephalopathy, and mild liver dysfunction sometimes accompanied by generalized seizures. The episodes can be triggered by varicella zoster virus (VZV), measles mumps rubella (MMR) attenuated vaccine, parainfluenza virus, and Epstein-Barr virus (EBV).
UniProt: Q13158
Gene ID: 8772
Synonyms: FADD protein Antibody
FADD_HUMAN Antibody
Fas (TNFRSF6) associated via death domain Antibody
Fas associated via death domain Antibody
Fas associating death domain containing protein Antibody
Fas associating protein Antibody
Fas associating protein with death domain Antibody
Fas TNFRSF6 associated via death domain Antibody
FAS-associated death domain protein Antibody
FAS-associating death domain-containing protein Antibody
GIG 3 Antibody
GIG3 Antibody
Growth inhibiting gene 3 protein Antibody
Growth-inhibiting gene 3 protein Antibody
H sapiens mRNA for mediator of receptor induced toxicity Antibody
Mediator of receptor induced toxicity Antibody
MGC8528 Antibody
MORT 1 Antibody
MORT1 Antibody
Protein FADD Antibody
Information: Target information shown above is from the UniProt Consortium.
Western blot analysis of extracts of HT1080 cell line, using FADD antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Total Citations (2)
Description: Rabbit polyclonal antibody to FADD (N188)
Application: WB, IHC
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human FADD.

£165 – £283

Description: Rabbit polyclonal antibody to FADD (Phospho-Ser190)
Application: WB, IHC
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Peptide sequence around phosphorylation site of Serine190(N-R-S(p)-G-A) derived from Mouse FADD.

£180 – £234

Description: Rabbit polyclonal antibody to FADD.
Application: WB, IHC
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

£148 – £372

Description: Rabbit polyclonal antibody to FADD (Ab-191)
Application: WB
Host: Rabbit
Reactivity: Human
Immunogen: Synthesized peptide derived from C-terminal of human FADD.

£180 – £234

Please Note: Anti-FADD Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A0759
Size Price Quantity
100µl £243
200µl £372

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe