Anti-FCGRT Antibody [FCGRT/2932] (A248538)

Mouse monoclonal [FCGRT/2932] antibody to FCGRT for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-FCGRT Antibody [FCGRT/2932]
Description
Mouse monoclonal [FCGRT/2932] antibody to FCGRT.
Specificity
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.
Applications
IHC-P
Dilutions
IHC-P: 2-4 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 24-215, of human FCGRT protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
FCGRT/2932
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
46 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-FCGRT Antibody [FCGRT/2932] - BSA and Azide free (A251720).
Synonyms
Alpha chain, Fc fragment of IgG, receptor transporter, alpha, FCGRN_HUMAN, FcRn, FcRn alpha chain, FCRN, alpha chain, IgG Fc fragment receptor transporter alpha chain, IgG Gc receptor, IgG receptor FcRn large subunit p51, IgG receptor FcRn large subunit p51 precursor, Immunoglobulin receptor, intestinal, heavy chain, Neonatal Fc receptor
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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