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Anti-GAB2 Antibody

Rabbit polyclonal antibody to GAB2 from ABclonal (A0619).
Name: Anti-GAB2 Antibody
Description: Rabbit polyclonal antibody to GAB2.
Applications: WB, FC
Dilutions: WB: 1:500 - 1:1000, FC: 1:20 - 1:50.
Reactivity: Human
Immunogen: A synthetic Peptide of human GAB2.
Protein Length: 676
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Sequence Similarities: Belongs to the GAB family.
Post-Translational Modification: Phosphorylated on tyrosine residue(s) by the thrombopoietin receptor (TPOR), stem cell factor receptor (SCFR), and T-cell and B-cell antigen receptors, gp130, IL-2R and IL-3R (By similarity). Phosphorylated upon stimulation of TNFRSF11A/RANK by TNFSF11/RANKL (By similarity). Phosphorylated upon EGF stimulation. Phosphorylated on tyrosine residues by HCK upon IL6 signaling.
Cellular Location: Cytoplasm. Cell membrane.
UniProt: Q9UQC2
Gene ID: 9846
Synonyms: GAB 2 Antibody
GAB2_HUMAN Antibody
Grb 2 associated binder 2 Antibody
GRB 2 associated binding protein 2 Antibody
Grb2 associated binder 2 Antibody
GRB2 associated binder 2 pp100 Antibody
GRB2 associated binding protein 2 Antibody
GRB2-associated binder 2 Antibody
GRB2-associated-binding protein 2 Antibody
Growth factor receptor bound protein 2 associated protein 2 Antibody
Growth factor receptor bound protein 2-associated protein 2 Antibody
KIAA0571 Antibody
p97 Antibody
PH domain containing adaptor molecule p97 Antibody
pp100 Antibody
Information: Target information shown above is from the UniProt Consortium.
Western blot analysis of extracts of MCF7 cells, using GAB2 antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Description: Rabbit polyclonal antibody to Gab2 (Phospho-Ser623)
Application: WB, IHC
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Peptide sequence around phosphorylation site of Serine 623(P-S-S(p)-P-S) derived from Human Gab2 .

£180 – £234

Description: Rabbit polyclonal antibody to Gab2 (Phospho-Tyr643)
Application: WB, IHC
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Peptide sequence around phosphorylation site of tyrosine 643(V-D-Y(p)-V-Q) derived from Human Gab2 .

£180 – £234

Description: Rabbit polyclonal antibody to Gab 2 (L617)
Application: WB, IHC
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 587-634 of Human Gab 2.

£165 – £283

Description: Rabbit polyclonal antibody to Gab2 (Ab-623)
Application: WB
Host: Rabbit
Reactivity: Human
Immunogen: Synthesized non-phosphopeptide derived from human Gab2 around the phosphorylation site of serine 623 (P-S-S(p)-P-S).

£180 – £234

Please Note: Anti-GAB2 Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A0619
Size Price Quantity
100µl £243
200µl £372

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe