Anti-GCET2 Antibody [HGAL/2373] (A277621)

Mouse monoclonal [HGAL/2373] antibody to GCET2 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-GCET2 Antibody [HGAL/2373]
Description
Mouse monoclonal [HGAL/2373] antibody to GCET2.
Specificity
This antibody recognizes a protein of kDa, which is identified as HGAL. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 1-200, of human GCET2 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
HGAL/2373
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
21 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-GCET2 Antibody [HGAL/2373] - BSA and Azide free (A278209).
Synonyms
GCAT2, Gcet, GCET2 germinal center expressed transcript 2, GCET2 germinal centre expressed transcript 2, Gcsam, GCSAM_HUMAN, Germinal center associated lymphoma, Germinal center associated lymphoma protein, Germinal center B cell associated protein 2, Germinal center B-cell-expressed transcript 2 protein, Germinal center expressed transcript 2, Germinal center-associated lymphoma protein, Germinal center-associated signaling and motility protein, Germinal centre associated lymphoma, Germinal centre associated lymphoma protein, Germinal centre B cell associated protein 2, Germinal centre expressed transcript 2, hGAL, M17, M17 L
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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