Recombinant Anti-Glutamine Synthetase Antibody [rGLUL/8621] (A315027)

$765

Recombinant mouse monoclonal [rGLUL/8621] antibody to Glutamine Synthetase for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Glutamine Synthetase Antibody [rGLUL/8621]
Description
Recombinant mouse monoclonal [rGLUL/8621] antibody to Glutamine Synthetase.
Specificity
Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.
Applications
IHC-P
Positive Control
Human brain, stomach or thyroid.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 1-200) of human GLUL protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
rGLUL/8621
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
42 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
cell proliferation-inducing protein 59, GLNA, GLNA_HUMAN, GLNS, GLUL, Glutamate ammonia ligase, Glutamate decarboxylase, Glutamate--ammonia ligase, glutamine synthase, GS, PIG 43, PIG 59, PIG43, PIG59, Proliferation inducing protein 43
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Recombinant Anti-Glutamine Synthetase Antibody [rGLUL/8621] (A315027)? Please let us know so that we can list the citation on this page.

Alternative products to Anti-Glutamine Synthetase Antibody [rGLUL/8621] (A315027)

Top