Anti-Glutamine Synthetase Antibody [GLUL/6600] - BSA and Azide free (A278219)

Mouse monoclonal [GLUL/6600] antibody to Glutamine Synthetase for WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Glutamine Synthetase Antibody [GLUL/6600] - BSA and Azide free
Description
Mouse monoclonal [GLUL/6600] antibody to Glutamine Synthetase.
Specificity
Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.
Applications
WB, IHC-P
Dilutions
WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivity
Human, Horse, Bovine
Immunogen
Recombinant fragment, around amino acids 50-250, of human Glutamine Synthetase. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
GLUL/6600
Isotype
IgG2bc
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
42 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Glutamine Synthetase Antibody [GLUL/6600] (A277631).
Synonyms
cell proliferation-inducing protein 59, GLNA, GLNA_HUMAN, GLNS, GLUL, Glutamate ammonia ligase, Glutamate decarboxylase, Glutamate--ammonia ligase, glutamine synthase, GS, PIG 43, PIG 59, PIG43, PIG59, Proliferation inducing protein 43
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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