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Anti-Granzyme B Antibody (Biotin)

 
Rabbit polyclonal antibody to Granzyme B (Biotin) from FabGennix (GRNZB.c-BIOTIN).
Overview
Name: Anti-Granzyme B Antibody (Biotin)
Description: Rabbit polyclonal antibody to Granzyme B (Biotin)
Applications: ELISA, IHC, IP, WB
Dilutions: DB: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:150; Immunoprecipitation: 1:150; Western Blot: 1:500
Reactivity: Human, Monkey
Immunogen: Synthetic peptide taken within amino acid region 50-100 on human endogenous Granzyme B protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Biotin
Concentration: 0.63 µg/µl in antibody stabilization buffer
Storage: -20⁰C for long term storage

Target
Function: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Sequence Similarities: Belongs to the peptidase S1 family. Granzyme subfamily.
Cellular Location: Cytoplasmic granule.

Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells.
UniProt: P10144
Synonyms: C11 Antibody
Cathepsin G like 1 Antibody
Cathepsin G-like 1 Antibody
CCPI Antibody
CGL 1 Antibody
CGL1 Antibody
CSP B Antibody
CSPB Antibody
CTLA-1 Antibody
CTLA1 Antibody
CTSGL1 Antibody
Cytotoxic serine protease B Antibody
Cytotoxic T lymphocyte associated serine esterase 1 Antibody
Cytotoxic T lymphocyte proteinase 2 Antibody
Cytotoxic T-lymphocyte proteinase 2 Antibody
Fragmentin 2 Antibody
Fragmentin-2 Antibody
GRAB_HUMAN Antibody
Granzyme 2 Antibody
Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1) Antibody
Granzyme-2 Antibody
GranzymeB Antibody
GRB Antibody
Gzmb Antibody
Hlp Antibody
Human lymphocyte protein Antibody
Lymphocyte protease Antibody
Protease, serine, B Antibody
SECT Antibody
T cell serine protease 1-3E Antibody
T-cell serine protease 1-3E Antibody
Information: Target information shown above is from the UniProt Consortium.


Related Products
Description: Rabbit polyclonal antibody to Granzyme B (Biotin)
Application: ELISA, IMM, WB
Host: Rabbit
Reactivity: Human, Monkey
Immunogen: Synthetic peptide taken within amino acid region 1-50 on human endogenous Granzyme B protein.

£429






Please Note: Anti-Granzyme B Antibody (Biotin) is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | GRNZB.c-BIOTIN
Size Price Quantity
100µg £429

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