Recombinant Anti-Growth Hormone Antibody [GH/8136R] (A315049)

Anti-Growth Hormone Antibody [GH/8136R]

Recombinant rabbit monoclonal [GH/8136R] antibody to Growth Hormone.

Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

Pituitary cells. Human pituitary tissue (IHC).

IHC: 1-2 µg/ml

Human

Recombinant full-length human GH1 protein.

Rabbit

Monoclonal

GH/8136R

IgG

Unconjugated

Protein A/G chromatography.

200 µg/ml

20 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

gH, GH-N, GH1, GHB5, GHN, Growth hormone 1, Growth hormone B5, Growth hormone, normal, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin, SOMA_HUMAN