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Anti-IgE Antibody

 
Mouse monoclonal (4C3) antibody to IgE from Absea Biotechnology (000104C03).
Overview
Name: Anti-IgE Antibody
Description: Mouse monoclonal (4C3) antibody to IgE.
Applications: ELISA, WB, Sandwich ELISA
Reactivity: Human
Immunogen: Recombinant human IgE.
Host: Mouse
Clonality: Monoclonal
Clone: 4C3
Isotype: IgG1
Conjugate: Unconjugated
Purification: IgG is purified through a Protein A column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location: Secreted. Cell membrane.
UniProt: P01854
Gene ID:
Synonyms: Igh2 Antibody
IGHE Antibody
IGHEP1 Antibody
Immunoglobulin heavy constant epsilon Antibody
Information: Target information shown above is from the UniProt Consortium.

Images
Sandwich ELISA - Anti-IgE Antibody from Absea Biotechnology (000104C03) - Antibodies.com
Sandwich ELISA using 4C3 coated plate and HRP conjugated 1A2.

Research Areas

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Please Note: Anti-IgE Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 000104C03
Size Price Quantity
100µg £178
200µg £259
1mg £682

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