Anti-Integrin beta 3 Antibody [Y2/51] (FITC) (A282015)

Anti-Integrin beta 3 Antibody [Y2/51] (FITC)

Mouse monoclonal [Y2/51] antibody to Integrin beta 3 (FITC).

This antibody recognises CD61, a ~105 kDa glycoprotein, also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51.CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin.

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

PHA stimulated peripheral blood cells.

Mouse

Monoclonal

Y2/51

IgG1

Protein A affinity chromatography of tissue culture supernatant.

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Mouse anti Human CD61 antibody, clone Y2/51 recognizes CD61, a ~105 kDa glycoprotein, also known as integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51.CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin.

BDPLT16, BDPLT2, CD 61, CD61, CD61 antigen, GP3A, GPIIIa, GT, HPA 1, HPA 4, Integrin beta 3 (platelet glycoprotein IIIa antigen CD61), Integrin beta chain beta 3, Integrin beta-3, ITB3_HUMAN, ITG B3, ITGB 3, ITGB3, NAIT, Platelet fibrinogen receptor beta subunit, Platelet fibrinogen receptor, beta subunit, Platelet glycoprotein IIIa, Platelet glycoprotein IIIa precursor, Platelet membrane glycoprotein IIIa, PTP

This product is for research use only. It is not intended for diagnostic or therapeutic use.