Anti-MCM2 Antibody [MCM2/3678] - BSA and Azide free (A278291)

Mouse monoclonal [MCM2/3678] antibody to MCM2 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-MCM2 Antibody [MCM2/3678] - BSA and Azide free
Description
Mouse monoclonal [MCM2/3678] antibody to MCM2.
Specificity
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000 full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 650-750, of human MCM2 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
MCM2/3678
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
102 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-MCM2 Antibody [MCM2/3678] (A277703).
Synonyms
BM28, CCNL 1, CCNL1, CDC like 1, cdc19, CDCL 1, CDCL1, Cell devision cycle like 1, Cyclin like 1, D3S3194, DNA replication licensing factor MCM2, KIAA0030, MCM 2, MCM2 minichromosome maintenance deficient 2 mitotin, MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae), MCM2 minichromosome maintenance deficient 2, mitotin, MCM2_HUMAN, MGC10606, Minichromosome maintenance complex component 2, Minichromosome maintenance deficient 2 (mitotin), Minichromosome maintenance deficient 2 mitotin, Minichromosome maintenance protein 2, Minichromosome maintenance protein 2 homolog, Mitotin, Nuclear protein BM28, OTTHUMP00000216047, OTTHUMP00000216050
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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