Anti-MCM5 Antibody [CRCT5.1] (A280144)

Anti-MCM5 Antibody [CRCT5.1]

Mouse monoclonal [CRCT5.1] antibody to MCM5.

This antibody recognises human Mcm-5 (minichromosome maintenance protein 5), also known as DNA replication licensing factor MCM5 or P1-CDC46. Mcm5 is a nuclear protein of ~95kDa with an important role in the control of DNA replication. Immunocytochemical assessment of Mcm5 expression may be of value in improving the accuracy of cervical smear testing for the detection of malignancy.

WB, IHC-P

IHC-P 1: 1:50 for 20 µg, 1:25 for 0.1 mg - 1:1,000 for 20 µg, 1:100 for 0.1 mg

Human

Bacterially expressed human Mcm5.

Mouse

Monoclonal

CRCT5.1

IgG2b

Unconjugated

Protein A affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human Mcm5 antibody, clone CRCT5.1 recognizes human Mcm-5 (minichromosome maintenance protein 5), also known as DNA replication licensing factor MCM5 or P1-CDC46. Mcm5 is a nuclear protein of ~95kDa with an important role in the control of DNA replication (Snyder et al. 2005).Immunocytochemical assessment of Mcm5 expression may be of value in improving the accuracy of cervical smear testing for the detection of malignancy (Murphy et al. 2004).

CDC 46, CDC46, CDC46 homolog, Cell division cycle 46, DNA replication licensing factor, DNA replication licensing factor MCM 5, DNA replication licensing factor MCM5, MCM 5, MCM5_HUMAN, MGC5315, Minichromosome maintenance complex component 5, Minichromosome maintenance deficient (S. cerevisiae) 5, Minichromosome maintenance deficient 5, Minichromosome maintenance deficient protein 5, P1 CDC46, P1-CDC46