Anti-MED22 Antibody [PCRP-MED22-1E4] (A277816)

Mouse monoclonal [PCRP-MED22-1E4] antibody to MED22 for ELISA, IF, IP, Flow Cytometry and WB.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-MED22 Antibody [PCRP-MED22-1E4]
Description
Mouse monoclonal [PCRP-MED22-1E4] antibody to MED22.
Specificity
Med22 is a subunit of the RNA polymerase II (Pol II) transcriptional mediator complex. The mediator complex is a coactivator involved in the regulated transcription of Pol II-dependent genes. Functioning as a bridge to convey information from gene-specific regulatory proteins to the basal Pol II transcription machinery, the mediator complex is recruited to promoter regions by directly interacting with regulatory proteins. The mediator complex also serves as a scaffold for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors. Med22 (mediator complex subunit 22), also known as SURF5 (surfeit locus protein 5), is a ubiquitously expressed 200 amino acid nuclear protein that is one of several components of the mediator complex. There are two isoforms of Med22 that are produced as a result of alternative splicing events.
Applications
ELISA, IF, IP, Flow Cytometry, WB
Dilutions
IF: 0.5-2 µg/ml, IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 0.5-2 µg/million cells, WB: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human MED22 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-MED22-1E4
Isotype
IgG2c
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
22 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MED22 Antibody [PCRP-MED22-1E4] - BSA and Azide free (A278404).
Synonyms
MED22_HUMAN, MED24, Mediator complex subunit 22, Mediator of RNA polymerase II transcription subunit 22, OTTHUMP00000022480, OTTMUSP00000012503, RGD1564893, Surf 5, Surf-5, SURF5, Surfeit 5, Surfeit locus protein 5
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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