Recombinant Anti-Melanoma Antibody [rMLANA/8134] - BSA and Azide free (A316679)

$765

Recombinant mouse monoclonal [rMLANA/8134] antibody to Melanoma for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Melanoma Antibody [rMLANA/8134] - BSA and Azide free
Description
Recombinant mouse monoclonal [rMLANA/8134] antibody to Melanoma.
Specificity
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Applications
IHC-P
Positive Control
SK-MEL-13 or SK-MEL-19 melanoma cell lines. Melanomas.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human MART-1 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
rMLANA/8134
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
20-22 kDa (doublet)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Antigen LB39 AA, Antigen SK29 AA, MART1, melan A, Melan A protein, Melanoma antigen recognized by T-cells 1 , Monophenol monooxygenase, Tumor rejection antigen AB, tyrosinase
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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