Anti-MMP3 Antibody [1B4] (A249367)

Mouse monoclonal [1B4] antibody to MMP3 for ELISA.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-MMP3 Antibody [1B4]
Description
Mouse monoclonal [1B4] antibody to MMP3.
Specificity
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
Applications
ELISA
Dilutions
ELISA: 2-4 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, corresponding to amino acids 317-327, of human MMP3 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
1B4
Isotype
IgG3
Light Chains
lambda
Conjugate

Unconjugated

Purification
Protein A chromatography.
Concentration
200 µg/ml
Molecular Weight
57 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Store at 4°C.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MMP3 Antibody [1B4] - BSA and Azide free (A252547).
Synonyms
CHDS6, Matrix metalloproteinase 3, Matrix metalloproteinase-3, MGC126102, MGC126103, MGC126104, MMP 3, MMP-3, MMP3_HUMAN, Proteoglycanase , SL-1, SL1 , STMY, STMY1, STR1, Stromelysin 1, Stromelysin-1, Transin 1, Transin-1
Isotype Controls
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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