Anti-MMP9 Antibody [MMP9/2477] (A249375)

Mouse monoclonal [MMP9/2477] antibody to MMP9 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

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Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
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Email
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Highlighted products for Anti-MMP9 Antibody

Name
Anti-MMP9 Antibody [MMP9/2477]
Description
Mouse monoclonal [MMP9/2477] antibody to MMP9.
Specificity
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is down-regulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 22-166, of human MMP9 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
MMP9/2477
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A chromatography.
Concentration
200 µg/ml
Molecular Weight
92 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-MMP9 Antibody [MMP9/2477] - BSA and Azide free (A252555).
Synonyms
82 kDa matrix metalloproteinase-9, 92 kDa gelatinase, 92 kDa type IV collagenase, CLG 4B, CLG4B, Collagenase Type 4 beta, Collagenase type IV 92 KD, EC 3.4.24.35, Gelatinase 92 KD, Gelatinase B, Gelatinase beta, GelatinaseB, GELB, Macrophage gelatinase , MANDP2, Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase), Matrix Metalloproteinase 9, MMP 9, MMP-9, MMP9_HUMAN, Type V collagenase
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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