Anti-MUC4 Antibody [MUC4/3105] - BSA and Azide free (A252609)

Mouse monoclonal [MUC4/3105] antibody to MUC4 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-MUC4 Antibody [MUC4/3105] - BSA and Azide free
Description
Mouse monoclonal [MUC4/3105] antibody to MUC4.
Specificity
The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100%) and sensitive (90%) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 1730-1864, of human MUC4 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
MUC4/3105
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
235 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-MUC4 Antibody [MUC4/3105] (A249429).
Synonyms
Ascites sialoglycoprotein, Ascites sialoglycoprotein 1, Ascites sialoglycoprotein 2, ASGP, ASGP-1, ASGP-2, HSA276359, MUC 4, MUC-4, MUC4_HUMAN, Mucin 4, Mucin 4 cell surface associated, Mucin 4 tracheobronchial, Mucin-4 beta chain, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucin, Tracheobronchial mucin Fragment
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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