Anti-Myelin Basic Protein Antibody [22] (A278728)

Anti-Myelin Basic Protein Antibody [22]

Mouse monoclonal [22] antibody to Myelin Basic Protein.

This antibody recognises an epitope between amino acids 67 and 74 of human myelin basic protein. Also expected to recognize isoforms 1 and 2 (UniProt: P02686). The N-terminal region of MBP is highly conserved and this clone is expected to be broadly species cross reactive for isoforms maintaining the N-terminal region.

IHC-P, IHC-Fr

Human

Human myelin basic protein.

Mouse

Monoclonal

22

IgG2b

Unconjugated

Lot Specific

Liquid

Supplied in <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Human myelin basic protein is also known as MBP, Myelin A1 protein or Myelin membrane encephalitogenic protein. MBP is a 304 amino acid ~33 kDa abundant component of the myelin membrane. There are 6 potential isoforms of MBP generated by alternative splicing, 4 of which lack the N-terminal region containing the immunogen sequence.

GDB, Golli MBP, Golli MBP; myelin basic protein, Hemopoietic MBP, HMBPR, HUGO, MBP, MBP_CAVPO, MBP_HUMAN, MGC99675, MLD, Myelin A1 protein, Myelin A1 Protein, basic, Myelin Deficient, Myelin membrane encephalitogenic protein, OTTHUMP00000163776, OTTHUMP00000174387, OTTHUMP00000174388, SHI, Shiverer, SP