Anti-pan Cytokeratin Antibody [Cocktail PAN-CK] (A250892)

Anti-pan Cytokeratin Antibody [Cocktail PAN-CK]

Mouse monoclonal [Cocktail PAN-CK] antibody to pan Cytokeratin.

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 55kDa (CK7); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 46kDa (CK17); 45kDa (CK18) and 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.

Flow Cytometry, IHC-P

Flow Cytometry: 1-2 µg/million cells, IHC-P: 1-2 µg/ml

Human, Monkey, Bovine, Canine, Rabbit, Mouse, Rat, Chicken

Human epidermal keratin.

Mouse

Monoclonal

Cocktail PAN-CK

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

40-67 kDa (Multiple)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-pan Cytokeratin Antibody [Cocktail PAN-CK] - BSA and Azide free (A254072).