Anti-Parvalbumin Antibody [PVALB/7601] (A315462)

Anti-Parvalbumin Antibody [PVALB/7601]

Mouse monoclonal [PVALB/7601] antibody to Parvalbumin.

The family of EF-hand type Ca2+-binding proteins includes calbindin (previously designated vitamin D-dependent Ca2+-binding protein), S-100 plays a significant role in muscle relaxation. OCM was originally thought to have expression restricted to neoplastic tissues, early embryonic cells and certain tumor cell lines. Recent research shows that OCM is also expressed and secreted by macrophages where, in the retina it binds to retinal ganglion cells (RGCs) and functions to promote axon regeneration. OCM has also been detected in the auditory sensory cells of the organ of Corti in mammals. In humans, two different loci on chromosome 7 have been identified as OCM and OCM-like (LOC4951). These genes encode proteins 109 amino acids in length which share 99% sequence identity.

Human brain or kidney.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-110) of human PVALB protein. The exact sequence is proprietary.

Mouse

Monoclonal

PVALB/7601

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

12 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

D22S749, MGC116759, Parvalbumin alpha, PRVA_HUMAN, PVALB