Anti-Podoplanin / gp36 Antibody [4D5aE5E6] (A279370)

Anti-Podoplanin / gp36 Antibody [4D5aE5E6]

Mouse monoclonal [4D5aE5E6] antibody to Podoplanin / gp36.

This antibody recognises human podoplanin also known as gp36, Aggrus, PA2.26 antigen or T1 alpha. Podoplanin is a 140 amino acid ~36 kDa single pass, type I cell membrane-associated glycoprotein, with a broad spectrum of distribution. Podoplanin is strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver.Podoplanin is preferentially expressed on lymphatic and absent on blood endothelium and therefore Mouse anti Human podoplanin antibody, clone 4D5aE5E6 is readily able to distinguish between lymphatic vessels and blood vasculature. Podoplanin is reported to be a reliable indicator of tumour lymphangiogenesis.

IHC-P, IHC-Fr

IHC-Fr: 0.75 µg/ml - 2 µg/ml

Human

ORF human podoplanin ectodomain expressed in E.coli.

Mouse

Monoclonal

4D5aE5E6

IgG1

Unconjugated

Protein G affinity chromatography of tissue culture supernatant.

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human podoplanin antibody, clone 4D5aE5E6 recognizes human podoplanin also known as gp36, Aggrus, PA2.26 antigen or T1 alpha. Podoplanin is a 140 amino acid ~36 kDa single pass, type I cell membrane-associated glycoprotein, with a broad spectrum of distribution. Podoplanin is strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver.Podoplanin is preferentially expressed on lymphatic and absent on blood endothelium (Breiteneder-Geleff et al. 1999) and therefore Mouse anti Human podoplanin antibody, clone 4D5aE5E6 is readily able to distinguish between lymphatic vessels and blood vasculature. Podoplanin is reported to be a reliable indicator of tumour lymphangiogenesis (Kitano et al. 2010).

Aggrus, Glycoprotein 36, Glycoprotein 36 KD, gp 36, GP 38, GP 40, gp36, GP38, GP40, HT1A 1, HT1A1, hT1alpha 1, hT1alpha 2, hT1alpha1, hT1alpha2, Lung type I cell membrane associated glycoprotein, Lung type I cell membrane associated glycoprotein isoform a, Lung type I cell membrane associated glycoprotein T1A 2, OTS 8, OTS8, OTTHUMP00000009640, OTTHUMP00000044504, PA2.26, PA2.26 antigen, Pdpn, PDPN_HUMAN, Podoplanin, PSEC0003, PSEC0025, T1 alpha, T1 ALPHA GENE, T1-alpha, T1A, T1A 2, TI1A, TIA 2, TIA2