Vasculature markers are specific proteins commonly used to label and identify various components of the vascular system, including blood vessels and associated cells. These markers play important roles in cardiovascular research and medical applications thereof, helping researchers and clinicians to study and understand vascular development, function, and disease processes. Some commonly used vasculature markers include: 1) CD31 (PECAM-1). CD31, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), is a widely used endothelial cell marker. It is found on the surface of endothelial cells and is often used to identify blood vessels in histological sections. CD31 is also involved in cell-cell adhesion and platelet adhesion to endothelial cells; 2) VE-Cadherin (CD144). Vascular endothelial cadherin (VE-Cadherin) is a cell adhesion molecule that is highly specific to endothelial cells. It plays an important role in maintaining the integrity of endothelial cell junctions, contributing to the formation of both tight and adherens junctions. VE-Cadherin is often used as a marker for endothelial cell monolayers and is important in studies of angiogenesis and vascular permeability; 3) vWF (von Willebrand Factor). Von Willebrand factor is a glycoprotein produced by endothelial cells and megakaryocytes. It is involved in platelet adhesion and aggregation, as well as serving as a marker of endothelial cells. vWF is often used in immunohistochemistry to label endothelial cells and identify blood vessels; 4) SMA (Smooth Muscle Actin). Smooth muscle actin is a cytoskeletal protein expressed predominantly in smooth muscle cells. It is used as a marker to identify the presence of smooth muscle cells in blood vessel walls and other tissues. SMA staining is commonly employed to distinguish between different layers of blood vessels and to study vascular remodelling; 5) Desmin. Desmin is an intermediate filament protein found in various types of muscle cells, including vascular smooth muscle cells. It is used to identify and label smooth muscle cells in blood vessel walls, particularly in situations where SMA staining might not be appropriate; 6) Endoglin (CD105). Endoglin is a co-receptor for TGF-beta and is highly expressed on proliferating endothelial cells. It is a marker of active angiogenesis and can be used to study tumour vasculature and other angiogenesis-related processes; 7) Tie2 (TEK). Tie2 is a receptor tyrosine kinase (RTK) expressed primarily on endothelial cells. It is involved in angiopoietin signalling, which plays a role in regulating angiogenesis and vascular stability. Tie2 is used as a marker for endothelial cells and to study the interactions between endothelial cells and their microenvironment. Finally, Flk-1 (VEGFR-2) is a receptor for vascular endothelial growth factor (VEGF). It is expressed on endothelial cells and is a key regulator of angiogenesis. Flk-1 is commonly used as a marker for endothelial cells and to study the effects of VEGF signalling. We provide a wide product catalogue of research reagents for studying vasculature markers, including Myeloperoxidase antibodies, alpha smooth muscle Actin antibodies, Elastin antibodies, Myeloperoxidase ELISA Kits, and Elastin ELISA Kits. Explore our full vasculature markers product range below and discover more, for less. Alternatively, you can explore our Arterial and Pulmonary product ranges.