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Anti-RAB11B Antibody

 
Rat monoclonal (KT80) antibody to RAB11B from Absea Biotechnology (061008G04).
Overview
Name: Anti-RAB11B Antibody
Description: Rat monoclonal (KT80) antibody to RAB11B.
Applications: WB, IF
Reactivity: Mouse
Immunogen: Recombinant mouse RAB11B.
Amino Acid Start: 177
Amino Acid End: 420
Host: Rat
Clonality: Monoclonal
Clone: KT80
Isotype: IgG2a
Conjugate: Unconjugated
Purification: Antibody is purified from culture supernatant using a protein G column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.
Tissue Specificity: Abundantly expressed in brain, heart and testis. Also detected in kidney and pancreatic islets.
Sequence Similarities: Belongs to the small GTPase superfamily. Rab family.
Post-Translational Modification: Citrullinated by PADI4.
Cellular Location: Recycling endosome membrane. Cytoplasmic vesicle > Secretory vesicle > Synaptic vesicle membrane. Cytoplasmic vesicle > Phagosome membrane.

Recruited to phagosomes containing S.aureus.
UniProt: P46638
Gene ID: 19326
Synonyms: GTP binding protein YPT3 Antibody
GTP-binding protein ypt3 Antibody
H YPT3 Antibody
H-YPT3 Antibody
RAB 11A Antibody
Rab11 Antibody
RAB11B member RAS oncogene family Antibody
RAB11B, member of RAS oncogene family Antibody
Ras related protein Rab 11B Antibody
RAS-associated protein RAB11B Antibody
Ras-related protein Rab-11B Antibody
RB11B_HUMAN Antibody
YPT3 Antibody
Information: Target information shown above is from the UniProt Consortium.

Related Products
Description: Rat monoclonal (KT81) antibody to RAB11B.
Application: WB, IF
Host: Rat
Isotype: IgG2b
Reactivity: Mouse

£186 – £730





Description: Rabbit polyclonal antibody to RAB11B.
Application: WB, IHC
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat

£243 – £372

Description: Rabbit Polyclonal Antibody to RAB11B-Specific
Application: ELISA, WB, IHC
Host: Rabbit
Isotype: IgG
Immunogen: RAB11B, member RAS oncogene family

£241






Please Note: Anti-RAB11B Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 061008G04
Size Price Quantity
100µg £186
200µg £273
1mg £730

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