Anti-Retinol Binding Protein Antibody [G4E4] (A249837)

Anti-Retinol Binding Protein Antibody [G4E4]

Mouse monoclonal [G4E4] antibody to Retinol Binding Protein.

This antibody recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.

IHC-P: 1-2 µg/ml

Human, Chimpanzee, Monkey, Goat, Rabbit, Rat, Mouse

Native Retinol Binding Protein-1 purified from human plasma.

Mouse

Monoclonal

G4E4

IgG1

Unconjugated

Protein A/G chromatography.

200 µg/ml

21-25 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-Retinol Binding Protein Antibody [G4E4] - BSA and Azide free (A253017).