Anti-S100 Antibody [6G1] (A279494)

$480

Mouse monoclonal [6G1] antibody to S100 for WB and ELISA.

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-S100 Antibody [6G1]
Description
Mouse monoclonal [6G1] antibody to S100.
Specificity
This antibody recognises S100 protein derived from human brain tissue. It is a ~21 kDa acidic calcium-binding protein synthesised by astroglial cells. It can be found predominantly as two isoforms, the alpha-beta heterodimer (S100a) and the beta-beta homodimer (S100b). The S100 family of proteins have been implicated in a large variety of intracellular and extracellular regulatory activities, such as cellular energy metabolism, cytoskeleton modification, cell proliferation and differentiation. When glial cells are damaged, S100 protein is leaked into the extracellular matrix and cerebrospinal fluid, further releasing into the bloodstream. As such, S100 protein can be used as a sensitive and reliable marker for nervous system damage, such as after brain damage or acute stroke. recognises both S100a (alpha-beta) and S100b (beta-beta). Mouse anti Human S100 Protein antibody, clone 6G1 is sensitive to EDTA and other bivalent-binding agents. Better performance can be obtained in the presence of 5mM CaCl2 in assay buffers.
Applications
WB, ELISA
Reactivity
Human
Immunogen
Human brain S100 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
6G1
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein A affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human S100 Protein antibody, clone 6G1 recognizes S100 protein derived from human brain tissue. It is a ~21 kDa acidic calcium-binding protein synthesised by astroglial cells. It can be found predominantly as two isoforms, the alpha-beta heterodimer (S100a) and the beta-beta homodimer (S100b). The S100 family of proteins have been implicated in a large variety of intracellular and extracellular regulatory activities, such as cellular energy metabolism, cytoskeleton modification, cell proliferation and differentiation. When glial cells are damaged, S100 protein is leaked into the extracellular matrix and cerebrospinal fluid, further releasing into the bloodstream. As such, S100 protein can be used as a sensitive and reliable marker for nervous system damage, such as after brain damage or acute stroke. Mouse anti Human S100 Protein antibody, clone 6G1 recognizes both S100a (alpha-beta) and S100b (beta-beta). Mouse anti Human S100 Protein antibody, clone 6G1 is sensitive to EDTA and other bivalent-binding agents. Better performance can be obtained in the presence of 5mM CaCl2 in assay buffers.
Synonyms
Bpb, NEF, Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 alpha, S100 beta, S100 calcium binding protein A1, S100 calcium binding protein B, S100 calcium-binding protein A1, S100 protein alpha polypeptide, S100A, s100a1, S100B, S100beta, S10A1_HUMAN
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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