Recombinant Anti-Sarcomeric alpha Actinin Antibody [ACTN2/7041R] (A315605)

$765

Recombinant rabbit monoclonal [ACTN2/7041R] antibody to Sarcomeric alpha Actinin for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Sarcomeric alpha Actinin Antibody [ACTN2/7041R]
Description
Recombinant rabbit monoclonal [ACTN2/7041R] antibody to Sarcomeric alpha Actinin.
Specificity
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Applications
IHC-P
Positive Control
Human skeletal or cardiac muscle.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
A recombinant fragment (aa557-692) of human ACTN2 protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
ACTN2/7041R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
103 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Actin binding protein, Actinin alpha 2, ACTN 2, ACTN2, ACTN2_HUMAN, Alpha actinin 2, Alpha actinin skeletal muscle, Alpha actinin skeletal muscle isoform 2, Alpha-actinin skeletal muscle isoform 2, Alpha-actinin-2, CMD1AA, F actin cross linking protein, F-actin cross-linking protein
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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