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Anti-SMC2 Antibody

 
Rat monoclonal (KT74) antibody to SMC2 from Absea Biotechnology (160404G04).
Overview
Name: Anti-SMC2 Antibody
Description: Rat monoclonal (KT74) antibody to SMC2.
Applications: WB
Reactivity: Mouse
Immunogen: Recombinant mouse SMC2 (aa167 - aa409).
Amino Acid Start: 177
Amino Acid End: 420
Host: Rat
Clonality: Monoclonal
Clone: KT74
Isotype: IgG2a
Conjugate: Unconjugated
Purification: Antibody is purified from culture supernatant using a protein G column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target
Function: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).
Sequence Similarities: Belongs to the SMC family. SMC2 subfamily.
Cellular Location: Nucleus. Cytoplasm. Chromosome.

In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDC2, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase (By similarity).
UniProt: Q8CG48
Gene ID: 14211
Synonyms: CAP E Antibody
CAPE Antibody
Chromosome associated protein E Antibody
Chromosome-associated protein E Antibody
FLJ10093 Antibody
hCAP E Antibody
hCAP-E Antibody
hCAPE Antibody
PRO0324 Antibody
SMC 2 Antibody
SMC protein 2 Antibody
SMC-2 Antibody
SMC2 L1 Antibody
SMC2L1 Antibody
SMC2_HUMAN Antibody
Structural maintenance of chromosomes (SMC) family member chromosome associated protein E Antibody
Structural maintenance of chromosomes 2 Antibody
Structural maintenance of chromosomes 2 like 1 Antibody
Structural maintenance of chromosomes 2 yeast like 1 Antibody
Structural maintenance of chromosomes protein 2 Antibody
XCAP E homolog Antibody
XCAP-E homolog Antibody
XCAPE homolog Antibody
Information: Target information shown above is from the UniProt Consortium.


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Isotype: IgG
Reactivity: Human

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Description: Rabbit polyclonal antibody to SMC2
Application: WB
Host: Rabbit
Reactivity: Human
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Description: Rabbit polyclonal antibody to SMC2
Application: IHC
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human SMC2

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Please Note: Anti-SMC2 Antibody is for research use only. It is not intended for diagnostic of therapeutic use.
Antibodies.com | 160404G04
Size Price Quantity
100µg £186
200µg £273
1mg £730

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