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Anti-SNAP25 Antibody

Rabbit polyclonal antibody to SNAP25 from ABclonal (A0795).
Name: Anti-SNAP25 Antibody
Description: Rabbit polyclonal antibody to SNAP25.
Applications: WB
Dilutions: WB: 1:500 - 1:1000.
Reactivity: Human
Immunogen: A synthetic peptide of human SNAP25.
Protein Length: 206
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.
Tissue Specificity: Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
Involvement in Disease: Myasthenic syndrome, congenital, 18: A form of congenital myasthenic syndrome, a group of disorders characterized by failure of neuromuscular transmission, including pre-synaptic, synaptic, and post-synaptic disorders that are not of autoimmune origin. Clinical features are easy fatigability and muscle weakness affecting the axial and limb muscles (with hypotonia in early-onset forms), the ocular muscles (leading to ptosis and ophthalmoplegia), and the facial and bulbar musculature (affecting sucking and swallowing, and leading to dysphonia). The symptoms fluctuate and worsen with physical effort. CMS18 is an autosomal dominant presynaptic disorder clinically characterized by early-onset muscle weakness and easy fatigability associated with delayed psychomotor development and ataxia.
Sequence Similarities: Belongs to the SNAP-25 family.
Post-Translational Modification: Palmitoylated. Cys-85 appears to be the main site, and palmitoylation is required for membrane association (By similarity).
Cellular Location: Cytoplasm > Perinuclear region. Cell membrane. Cell junction > Synapse > Synaptosome.

Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane (By similarity).
UniProt: P60880
Gene ID: 6616
Synonyms: bA416N4.2 Antibody
Bdr Antibody
CMS18 Antibody
dJ1068F16.2 Antibody
FLJ23079 Antibody
HGNC:11132 Antibody
MGC105414 Antibody
MGC139754 Antibody
Resistance to inhibitors of cholinesterase 4 homolog Antibody
RIC 4 Antibody
RIC4 Antibody
SEC 9 Antibody
SEC9 Antibody
SNAP Antibody
SNAP 25 Antibody
SNAP-25 Antibody
SNAP-25B Antibody
SNP 25 Antibody
SNP25 Antibody
SNP25_HUMAN Antibody
sp Antibody
SUP Antibody
Super protein Antibody
Synaptosomal associated 25 kDa protein Antibody
Synaptosomal associated protein Antibody
Synaptosomal associated protein 25 Antibody
Synaptosomal associated protein 25kDa Antibody
Synaptosomal-associated 25 kDa protein Antibody
Synaptosomal-associated protein 25 Antibody
Synaptosomal-associated protein, 25-KD Antibody
Information: Target information shown above is from the UniProt Consortium.
Western blot analysis of extracts of SH-SY5Y cells, using SNAP25 antibody.
Please Note: All batches are extensively validated and are guaranteed to work as specified, however, QC data is not necessarily from the current lot on sale.
Total Citations (3)
Description: Goat polyclonal antibody to SNAP25.
Application: ELISA, WB, IHC
Host: Goat
Isotype: IgG
Reactivity: Human, Mouse

£205

Total Citations (1)
Description: Rabbit polyclonal antibody to SNAP25
Application: WB, IHC, ICC, IF, IP
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human SNAP25.

£220 – £366

Total Citations (1)
Description: Rabbit polyclonal antibody to SNAP 25 (E183)
Application: WB, IHC
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human SNAP 25.

£165 – £283

Description: Rabbit polyclonal antibody to SNAP25
Application: WB, IHC, IF, IP
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human SNAP25.

£234

Please Note: Anti-SNAP25 Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | A0795
Size Price Quantity
100µl £243
200µl £372

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Lead Time: Currently 4-6 Days
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