Anti-SOX11 Antibody [SOX11/7236] - BSA and Azide free (A278389)

Mouse monoclonal [SOX11/7236] antibody to SOX11 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-SOX11 Antibody [SOX11/7236] - BSA and Azide free
Description
Mouse monoclonal [SOX11/7236] antibody to SOX11.
Specificity
This antibody recognizes a protein of ~47kDa, identified as SOX11. This MAb is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5%-10% of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL, show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker for identifying true cyclin D1-negative MCL.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 50-200, of human SOX11 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
SOX11/7236
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
47 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-SOX11 Antibody [SOX11/7236] (A277801).
Synonyms
MRD27, SOX11_HUMAN, SRY (sex determining region Y) box 11, SRY related HMG box gene 11, SRY-box 11, Transcription factor SOX-11
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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