Anti-Syndecan-1 Antibody [SDC1/7183] (A315707)

$765

Mouse monoclonal [SDC1/7183] antibody to Syndecan-1 for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-Syndecan-1 Antibody [SDC1/7183]
Description
Mouse monoclonal [SDC1/7183] antibody to Syndecan-1.
Specificity
CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinomas.
Applications
IHC-P
Positive Control
Human tonsil or lymph node.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 1-250) of human CD138 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
SDC1/7183
Isotype
IgG1
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
85 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
CD138, CD138 antigen, CD_antigen, heparan sulfate proteoglycan fibroblast growth factor receptor, SDC, Sdc1, SDC1_HUMAN, SYND1, Syndecan, Syndecan 1, syndecan proteoglycan 1
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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