Anti-TDP43 Antibody [TARDP/349] - BSA and Azide free (A317098)

$765

Mouse monoclonal [TARDP/349] antibody to TDP43 for ELISA, WB and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com

Highlighted products for Anti-TDP43 Antibody

Name
Anti-TDP43 Antibody [TARDP/349] - BSA and Azide free
Description
Mouse monoclonal [TARDP/349] antibody to TDP43.
Specificity
TARDBP (TAR DNA binding protein), also known as TDP-43, is a nuclear protein that contains two RRM (RNA recognition motif) domains. Ubiquitously expressed with highest levels found in placenta, lung, pancreas, spleen and genital tract, TARDBP functions as a DNA-binding protein and specifically binds to the TAR DNA sequence motifs of HIV. Via this association with TAR motifs, TARDBP acts as a transcriptional repressor and inhibits HIV-1 transcription. TARDBP can also function as a negative regulator of splicing activity and is known to be involved in the splicing of CFTR (cystic fibrosis transmembrane receptor). In addition, TARDBP is a major component of ubiquitin-positive inclusion bodies that are prominent in many neurodegenerative diseases. This suggests that TARDBP may play a role in the development of neurodegenerative disorders. Due to alternative splicing events, various isoforms exist for TARDBP.
Applications
ELISA, WB, IHC-P
Positive Control
Human cerebrum or colon.
Dilutions
WB: 1-2 µg/ml, IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment within human TDP43 aa 200 to the C-terminus.
Host
Mouse
Clonality
Monoclonal
Clone ID
TARDP/349
Isotype
IgG1
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
44 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
ALS10, OTTHUMP00000002171, OTTHUMP00000002172, OTTHUMP00000002173, TADBP_HUMAN, TAR DNA binding protein, TAR DNA binding protein 43, TAR DNA-binding protein 43, TARDBP, TDP 43, TDP-43
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Anti-TDP43 Antibody [TARDP/349] - BSA and Azide free (A317098)? Please let us know so that we can list the citation on this page.

Alternative products to Anti-TDP43 Antibody [TARDP/349] - BSA and Azide free (A317098)

Top