Recombinant Anti-TdT Antibody [DNTT/4506R] - BSA and Azide free (A251532)

Recombinant rabbit monoclonal [DNTT/4506R] antibody to TdT for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-TdT Antibody [DNTT/4506R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [DNTT/4506R] antibody to TdT.
Specificity
Terminal deoxynucleotidyl transferase (TdT) is an unusual deoxynucleotide polymerizing enzyme with a molecular weight of about 58 kDa found normally only in B- and T-cell lymphoblasts/prelymphocytes. TdT generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Rare TdT-positive cells are regularly detected in thymus and bone marrow. Typically, TdT expression in the thymus is very variable from cell to cell since it is rapidly decreased in more mature T-cells. TdT-positive cells may occasionally be found in tonsils, lymph nodes and extranodal lymphoid tissue. Immunohistochemical detection of TdT has value in classification of malignant lymphomas and acute leukemias, particularly for the identification of pre-B and pre-T acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL).
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Synthetic peptide corresponding to amino acids within 1-100 of TdT.
Host
Rabbit
Clonality
Monoclonal
Clone ID
DNTT/4506R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
58 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-TdT Antibody [DNTT/4506R] (A248350).
Synonyms
Deoxynucleotidyltransferase terminal, DNA nucleotidylexotransferase, DNTT, Nucleosidetriphosphate DNA deoxynucleotidylexotransferase, TDT_HUMAN, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal deoxyribonucleotidyltransferase, Terminal transferase
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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