Anti-Tenascin C Antibody [TNC/4806] (A315716)

Anti-Tenascin C Antibody [TNC/4806]

Mouse monoclonal [TNC/4806] antibody to Tenascin C.

In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast, squamous cell, and lung carcinomas. Staining of normal fibroblasts serves as internal positive control (IHC).

IHC: 2-4 µg/ml

Human

Recombinant human full-length TNC protein.

Mouse

Monoclonal

TNC/4806

kappa

Unconjugated

Protein A/G chromatography.

200 µg/ml

210 kDa / 300 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

150 225, Cytotactin, Glioma associated extracellular matrix antigen, Glioma-associated-extracellular matrix antigen, GMEM, GP, GP 150 225, GP 150-225, Hexabrachion, HXB, JI, MGC167029, Miotendinous antigen, Myotendinous antigen, Neuronectin, Tenascin, Tenascin-C, Tenascin-C isoform 14/AD1/16, TenascinC, TENA_HUMAN, TN, TN C, TN-C, TNC