Anti-Thyroglobulin Antibody [5F9 (BGN/6E10)] (A279441)

Anti-Thyroglobulin Antibody [5F9 (BGN/6E10)]

Mouse monoclonal [5F9 (BGN/6E10)] antibody to Thyroglobulin.

This antibody recognises human thyroglobulin (Tg). Thyroglobulin is a 2768 amino acid ~670kDa homodimeric protein containing multiple thyroglobulin type 1 domains. Thyroglobulin is produced by the thyroid gland and is a precursor in the production of the thyroid hormones Triiodothyronine (T3) and Thyroxine (T4), important for regulating metabolic processes in the body (Uniprot: P01266).Mutations in the thyroglobulin gene can lead to developmental and autoimmune diseases including Thyroid dyshormonogenesis 3 and Autoimmune thyroid disease 3. Mouse anti Human Thyroglobulin antibody, clone 5F9 has been used successfully as a capture reagent in a sensitive sandwich ELISA for the detection of thyroglobulin in human serum and plasma samples.

8900-0700 is suitable for use as a capture antibody in a sandwich ELISA.

Human

Purified native human thyroglobulin.

Mouse

Monoclonal

5F9 (BGN/6E10)

IgG2a

Unconjugated

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human Thyroglobulin antibody, clone 5F9 recognizes human thyroglobulin (Tg). Thyroglobulin is a 2768 amino acid ~670kDa homodimeric protein containing multiple thyroglobulin type 1 domains. Thyroglobulin is produced by the thyroid gland and is a precursor in the production of the thyroid hormones Triiodothyronine (T3) and Thyroxine (T4), important for regulating metabolic processes in the body (Uniprot: P01266).Mutations in the thyroglobulin gene can lead to developmental and autoimmune diseases including Thyroid dyshormonogenesis 3 (Targovnik et al. 2010) and Autoimmune thyroid disease 3 (Ban et al. 2003).Mouse anti Human Thyroglobulin antibody, clone 5F9 has been used successfully as a capture reagent in a sensitive sandwich ELISA for the detection of thyroglobulin in human serum and plasma samples.

AITD 3, AITD3, hTG, TDH3, Tg, TGN, THYG_HUMAN