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Anti-TNF alpha Antibody

Mouse monoclonal (B1E4) antibody to Tumor Necrosis Factor alpha (HRP) from Anogen (MO-C40003T).
Name: Anti-TNF alpha Antibody
Description: Mouse monoclonal (B1E4) antibody to Tumor Necrosis Factor alpha (HRP).
Applications: ELISA
Reactivity: Human
Immunogen: Purified recombinant human TNF-α.
Host: Mouse
Clonality: Monoclonal
Clone: B1E4
Myeloma: Sp2/0-Ag14
Isotype: IgG1
Conjugate: HRP
Purity: Protein G affinity chromatagraphy.
Product Form: Liquid
Formulation: Supplied in 0.01M Phosphate Buffered Saline, pH 7.2, with 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Introduction: Tumor Necrosis Factor alpha (TNF-α) is a multifunctional pro-inflammatory cytokine, mainly secreted by activated macrophages. TNF-α was named for its remarkable ability to cause hemorrhagic necrosis of tumors in mice. It is implicated with a variety of biological procedures including systemic inflammation, cell proliferation, apoptosis, lipid metabolism, and coagulation. The pleiotropic attribute of TNF-α regulation is associated with its ability to trigger multiple signalling pathways simultaneously. It is well documented that TNF-α functions through its receptors, TNFR1 (p55) and TNFR2 (p75). TNF-α not only contributes to the immune response to bacterial, fungal, viral and parasitic invasions, but also functions in tissue remodeling, autoimmune-diseases and the necrosis of specific tumors. TNF-α hyper-expression in response to some bacterial components such as LPS can cause life threatening septic shock. Recombinant TNF-α, in combination with chemotherapy, has been applied for treatment of soft sarcomas, melanomas and other irresectable tumors. Anti-TNF-α therapy has been used for treatment of rheumatoid arthritis.
Synonyms: APC1 Antibody
APC1 protein Antibody
Cachectin Antibody
DIF Antibody
Differentiation inducing factor Antibody
Macrophage cytotoxic factor Antibody
Tnf Antibody
TNF superfamily, member 2 Antibody
TNF, macrophage derived Antibody
TNF, monocyte derived Antibody
TNF-a Antibody
TNF-alpha Antibody
TNFA Antibody
TNFSF2 Antibody
Tumor necrosis factor Antibody
Tumor necrosis factor alpha Antibody
Tumor necrosis factor ligand superfamily member 2 Antibody
Tumor Necrosis Factor, Membrane Form Antibody
Tumor necrosis factor, soluble form Antibody
Description: Mouse monoclonal (KT31) antibody to TNF alpha (HRP).
Application: sELISA 
Host: Mouse
Isotype: IgG2a
Reactivity: Human

£186 – £730

Please Note: Anti-TNF alpha Antibody is for research use only. It is not intended for diagnostic or therapeutic use.
Antibodies.com | MO-C40003T
Size Price Quantity
200µl £371

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Lead Time: Currently 4-6 Days
Shipping Information
  • £20 to United Kingdom
  • £35 to Europe