Anti-TNFSF9 Antibody [CD137L/1547] (Biotin) (A251231)

Mouse monoclonal [CD137L/1547] antibody to TNFSF9 (Biotin) for Flow Cytometry, IF and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com
Name
Anti-TNFSF9 Antibody [CD137L/1547] (Biotin)
Description
Mouse monoclonal [CD137L/1547] antibody to TNFSF9 (Biotin).
Specificity
TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
Applications
Flow Cytometry, IF, IHC-P
Dilutions
Flow Cytometry: 2-4 µg/million cells, IF: 2-4 µg/ml, IHC-P: 2-4 µg/ml
Reactivity
Human
Immunogen
Recombinant full-length human CD137L protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
CD137L/1547
Isotype
IgG2a
Light Chains
kappa
Conjugate

Biotin

Purification
Protein A/G chromatography.
Concentration
100 µg/ml
Molecular Weight
27 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
4 1BB L, 4 1BB ligand, 4 1BBL, 4-1BB ligand, 4-1BBL, Cd137l, Cd157l, Homolog of mouse 4 1BB L, Homolog of mouse 4 1BBL, ILA ligand (TNF related), Ly63l, Receptor 4 1BB ligand, TNF superfamily member 9, TNFL9_HUMAN, TNLG5A, Tumor necrosis factor (ligand) superfamily member 9, Tumor necrosis factor ligand 5A, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor superfamily member 9
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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