Anti-2B4 Antibody [2B4.69] (A279185)

Anti-2B4 Antibody [2B4.69]

Mouse monoclonal [2B4.69] antibody to 2B4.

This antibody recognises the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). CD244 is a 370 amino acid single pass type I transmembrane glycoprotein with two Ig-like V type domains. CD244 is a member of the SLAM family of receptors expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.CD244 was originally identified as an activating receptor on NK cells, The receptor may have a wide range of activities including NK cell activation, co-stimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of CD244 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.

IP, Flow Cytometry

Flow Cytometry: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

CD244 Fusion protein.

Mouse

Monoclonal

2B4.69

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human CD244 antibody, clone 2B4.69 recognizes the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). CD244 is a 370 amino acid single pass type I transmembrane glycoprotein with two Ig-like V type domains. CD244 is a member of the SLAM family of receptors expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.CD244 was originally identified as an activating receptor on NK cells, The receptor may have a wide range of activities including NK cell activation, co-stimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of CD244 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.

h2B4, NAIL, Natural killer cell receptor 2B4, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Signaling lymphocytic activation molecule 4, SLAM family member 4, SLAMF4