Anti-2B4 Antibody [2B4.69] - BSA and Azide free (A279186)

Anti-2B4 Antibody [2B4.69] - BSA and Azide free

Mouse monoclonal [2B4.69] antibody to 2B4.

This antibody recognises the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). CD244 is a 370 amino acid single pass type I transmembrane glycoprotein with two Ig-like V type domains. CD244 is a member of the SLAM family of receptors expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.CD244 was originally identified as an activating receptor on NK cells, The receptor may have a wide range of activities including NK cell activation, co-stimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of CD244 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.

Flow Cytometry, IP

Flow Cytometry: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Human

CD244 Fusion protein.

Mouse

Monoclonal

2B4.69

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Human CD244 antibody, clone 2B4.69 recognizes the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). CD244 is a 370 amino acid single pass type I transmembrane glycoprotein with two Ig-like V type domains. CD244 is a member of the SLAM family of receptors expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.CD244 was originally identified as an activating receptor on NK cells, The receptor may have a wide range of activities including NK cell activation, co-stimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of CD244 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.

h2B4, NAIL, Natural killer cell receptor 2B4, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Signaling lymphocytic activation molecule 4, SLAM family member 4, SLAMF4