Anti-Calretinin Antibody (A283253)

Anti-Calretinin Antibody

Sheep polyclonal antibody to Calretinin.

This antibody recognises calretinin, a ~29 kDa calcium binding protein found mostly in the central nervous system and retina. It is a cytoplasmic protein involved in the regulation of calcium concentration, which is important in the regulation of a large variety of neuronal functions, including neurotransmitter release, ionic channel permeability, enzyme activity, and gene transcription. Mice deficient in calretinin show impairment in motor coordination.Calretinin is a sensitive and specific marker for mast cells.

WB, IHC-Fr

IHC-Fr: 1:500, WB: 1:1,000

Guinea Pig, Rat, Human, Mouse, Primate

Purified guinea pig calretinin.

Sheep

Polyclonal

IgG

Lot Specific

Approximately 29 kDa in rat cerebellum.

Liquid

Supplied in TRIS Buffered Saline.

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Sheep anti calretinin antibody recognizes calretinin, a ~29 kDa calcium binding protein found mostly in the central nervous system and retina. It is a cytoplasmic protein involved in the regulation of calcium concentration, which is important in the regulation of a large variety of neuronal functions, including neurotransmitter release, ionic channel permeability, enzyme activity, and gene transcription. Mice deficient in calretinin show impairment in motor coordination.Calretinin is a sensitive and specific marker for mast cells.

29 kDa calbindin, CAB29, CALB2, CR