Recombinant Anti-CD31 Antibody [C31/8592R] - BSA and Azide free (A316043)

Anti-CD31 Antibody [C31/8592R] - BSA and Azide free

Recombinant rabbit monoclonal [C31/8592R] antibody to CD31.

CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Jurkat or THP-1 cells. Human tonsil or angiosarcoma.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 538-738) of human PECAM1 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

C31/8592R

kappa

Protein A/G chromatography.

1 mg/ml

~100 kDa (endothelium) / ~130 kDa (platelets)

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

EndoCAM, GPIIA', PECA1, PECAM-1, PECAM1, Platelet endothelial cell adhesion molecule