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Anti-CD40L Antibody - BSA and Azide free (A283009)

This product is discontinued

Anti-CD40L Antibody - BSA and Azide free (A283009) has been discontinued and is no longer available.

View all CD40L Antibodies.

Name
Anti-CD40L Antibody - BSA and Azide free
Description
Goat polyclonal antibody to CD40L.
Specificity
This antibody recognises the soluble form of human CD154, also designated CD40L (sCD40 Ligand), a member of the TNF receptor superfamily, comprising the full-length of the TNF homologous region of CD154.CD154 is expressed predominantly on activated CD4+ T lymphocytes, and acts as a costimulatory molecule in B cell differentiation/proliferation, immunoglobulin switching and germinal centre formation, through interaction with the CD40 receptor on B cells, and cytokines secreted by activated T cells.
Applications
WB, IHC-P, ELISA
Dilutions
ELISA: 0.5 - 2 µg/ml, IHC-P: 2.5 - 5.0 µg/ml, WB: 0.1 - 0.2 µg/ml
Reactivity
Human, Yeast
Immunogen
Recombinant human CD154.
Host
Goat
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
1 mg/ml after reconstitution.
Product Form
Lyophilized
Reconstitution
Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Goat anti Human CD154 antibody recognizes the soluble form of human CD154, also designated CD40L (sCD40 Ligand), a member of the TNF receptor superfamily, comprising the full-length of the TNF homologous region of CD154.CD154 is expressed predominantly on activated CD4+ T lymphocytes, and acts as a costimulatory molecule in B cell differentiation/proliferation, immunoglobulin switching and germinal centre formation, through interaction with the CD40 receptor on B cells, and cytokines secreted by activated T cells.
Synonyms
CD154, CD40 ligand, CD40-L, CD40LG, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5
Isotype Controls
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

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