Anti-EGFR Antibody [B1D8] (A248401)

Anti-EGFR Antibody [B1D8]

Mouse monoclonal [B1D8] antibody to EGFR.

This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF'induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.

IP, Flow Cytometry

IP: 1-2 µg / 500 µg protein lysate, Flow Cytometry: 1-2 µg/million cells

Human

This antibody does not cross react with Mouse or Rat.

Microsomes from A431 cells.

Mouse

Monoclonal

B1D8

IgG2a

kappa

Protein A/G chromatography.

200 µg/ml

~170 kDa (wild type) / ~145 kDa (vIII variant)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Epidermal growth factor receptor, ERBB, ERBB1, HER1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1