Recombinant Anti-EGFR Antibody [EGFR/6390R] - BSA and Azide free (A278562)

Anti-EGFR Antibody [EGFR/6390R] - BSA and Azide free

Recombinant rabbit monoclonal [EGFR/6390R] antibody to EGFR.

This antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment corresponding to the extracellular domain, around amino acids 25-645, of human EGFR protein. The exact sequence is proprietary.

Rabbit

Monoclonal

EGFR/6390R

IgG

Protein A/G chromatography.

1 mg/ml

~170 kDa (wild type) / ~145 kDa (vIII variant)

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-EGFR Antibody [EGFR/6390R] (A277974).

Epidermal growth factor receptor, ERBB, ERBB1, HER1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1