Recombinant Anti-EGFR Antibody [GFR/4563R] (A248411)

Anti-EGFR Antibody [GFR/4563R]

Recombinant rabbit monoclonal [GFR/4563R] antibody to EGFR.

This antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

IHC-P: 1-2 µg/ml

Human

Synthetic peptide corresponding to amino acids within 1050-1150 of EGFR.

Rabbit

Monoclonal

GFR/4563R

IgG

200 µg/ml

134 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-EGFR Antibody [GFR/4563R] - BSA and Azide free (A251593).

Epidermal growth factor receptor, ERBB, ERBB1, HER1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1